Searchable abstracts of presentations at key conferences in endocrinology

ea0052oc2 | (1) | UKINETS2017

Systematic evaluation of the immune microenvironment of neuroendocrine tumours

Vesely Clare , Childs Alexa , Wong Yien Ning Sophia , Ogunbiyi Olagunju , Gander Amir , Luong Tu Vinh , Thirlwell Chrissie , Caplin Martyn , Peggs Karl , Marafioti Teresa , Quezada Sergio A. , Meyer Tim

Background: Immunotherapy is currently being explored in many tumour types with encouraging results, but has not yet been evaluated in neuroendocrine tumours (NET). Our aim is to characterise the immune landscape of NET and determine which immune-modulatory pathways control the tumour infiltrating lymphocytes (TILs) in order to develop a rational approach for immunotherapy in this tumour type.Methods: Peripheral blood and fresh tissue was obtained from c...